Phd-student in immunopathology: the role of macrophages in neurodegeneration in MS
Job description
You will be a PhD student within the Departments of Molecular Cell Biology and Immunology and Pathology in which excellent immunological research is performed with a focus on molecular and cellular interactions and in which pathological studies are performed on human tissues.
Within your project, you will investigate how macrophages and microglia (the resident brain macrophages) are involved in neurodegeneration and neuroprotection. You will use in vitro studies to examine different ways of activating macrophages with the aim of identifying pathways involved in neurodegeneration process and pathways that might identify novel neuroprotective strategies. For this you will make use of a wide range of immunological, cell biological and histopathological techniques. Findings from the in vitro studies will be compared to human disease by examining the pathways in human tissue samples frrm people with MS. You will verify your findings using in vitro studies and animal studies where appropriate.
Besides the practical work in the lab, you are responsible for data analysis and writing research papers. You will closely collaborate with other researchers within the MS Center. A PhD thesis will be the result of your 4 years study.
Requirements
You have a master’s degree in medical biology (or related study) with specific interest in neurobiology and or immunology. Furthermore, you have
- Experience with cell biological techniques, including tissue culture
- Experience with immunohistochemistry.
Since you will participate in an ambitious research team, you:
- Are a highly motivated and creative student
- Have with excellent communication skills
- Are a team player.
Conditions of employment
If you decide to devote your skills and knowledge by working for VUmc, we are pleased to give you excellent working conditions in return. Whether you have a full – time or part-time position with us, you benefit from many attractive fringe benefits. Examples of our benefits are:
- Year-end bonus; In addition to your salary you will receive an annual year-end bonus of 8.3% of your gross monthly salary.
- Good pension plan (ABP), the pension is 20% of your gross salary, of which 14% is paid by VUmc.
- Additional Personal budget, this budget is for your own development, i.e. work-life balance, training
and vitality.
- Contribution to your travel expenses. When you use public transport for commuting you get a minimum of 50% reduction on your -subscription.
- Collective discounts on various insurances
- Additional benefits; VUmc employees get discounts at various businesses, restaurants or hotels. For example: Cheap Tickets, Fortis, and Polectro Opticians Pearl Plaza. You are also eligible for discount sports in the gym on the VU campus.
For all our fringe benefits, please visit:
Contract type
Temporary
Organisation
VU medisch centrum
Werken bij VU medisch centrum is werken op academisch niveau, in een informele en open sfeer, met vrijheid en verantwoordelijkheid. Je maakt deel uit van een organisatie waar meer dan zesduizend betrokken en bevlogen medewerkers samen werken aan beter maken en beter worden.
We richten ons op patiëntenzorg, opleidingen en wetenschappelijk onderzoek. Het medisch wetenschappelijk onderzoek VU medisch centrum staat in de top drie van de UMC’s. Al die kennis en het toepassen ervan is gericht op beter maken en beter worden. Zo dragen we bij aan de medische kennis van morgen.
Voor meer informatie over VU medisch centrum als werkgever, ga naar: www.vumc.nl/werken.
Department
MS centrum
The MS Center Amsterdam of the VU university medical center is a multidisciplinary center for research in multiple sclerosis (MS). The center has an excellent international reputation in both research and clinical studies and is a proven reliable source of scientific information about MS. Within the center more than 60 researchers of different disciplines cooperate to research the cause of and to develop a cure for MS. The combination of fundamental/basic and clinical research allows us to quickly apply new research developments to the diagnostics and treatment of MS. The MS Center Amsterdam offers young talented researchers an education in the neuroscience of MS from experts with international reputations.
The program grant, of which this vacancy is part, will examine the major topic of how neurodegeneration occurs in MS and how to develop therapies of neuroprotection. This prestigious grant is provided by the Dutch MS Research Foundation. You will participate in an ambitious research team for finding new strategies to treat MS.
Additional information
Sandra Amor
5809
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